Biomolecular structure prediction is now often run at proteome scale, where the goal is to move an entire worklist through the pipeline efficiently. NVIDIA...

Biomolecular structure prediction is now often run at proteome scale, where the goal is to move an entire worklist through the pipeline efficiently. NVIDIA BioNeMo Inference Runtime (BioIR) helps accelerate supported biomolecular structure-prediction models on NVIDIA GPUs while keeping the familiar PyTorch workflow. It uses optimized kernels and, where applicable, CUDA Graphs to speed model…

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Every NVIDIA CUDA Toolkit release adds functionality and performance improvements that help developers get more from NVIDIA GPUs and the broader NVIDIA software...

Every NVIDIA CUDA Toolkit release adds functionality and performance improvements that help developers get more from NVIDIA GPUs and the broader NVIDIA software platform. CUDA Toolkit 13.4 adds support for Windows on Arm. CUDA applications have long been supported on Arm platforms through Linux; this release extends that capability to the Windows on Arm platform.

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Agentic AI is changing how research is done. AI scientists can read papers, propose hypotheses, call models, and determine which experiments to prioritize next....

Agentic AI is changing how research is done. AI scientists can read papers, propose hypotheses, call models, and determine which experiments to prioritize next. First proving their value in software engineering, coding agents now write, test, and ship production code. Scientific research can be more demanding and iterative. Researchers continually evaluate evidence, refine hypotheses…

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A perception stack is shaped by the vehicle that carries it. Move the same software to a new carline—for example, from an SUV to a sedan or another vehicle...

A perception stack is shaped by the vehicle that carries it. Move the same software to a new carline—for example, from an SUV to a sedan or another vehicle variant in the portfolio—and its perception of the world changes. The sensor placement, calibration, fields of view, occlusions, body geometry, timing, and coverage all shift. A traffic light may appear in a different part of the frame.

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Navigation enables a robot to turn perception and motion into purposeful autonomy. Unlike locomotion, which produces stable movement, navigation must be used to...

Navigation enables a robot to turn perception and motion into purposeful autonomy. Unlike locomotion, which produces stable movement, navigation must be used to continuously localize the robot, interpret changing surroundings, select a route, and avoid obstacles to reach a goal safely. Moving this capability to a new robot or scene can require new data, simulation assets, robot interfaces…

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Use AdaptGrow, a GPU-accelerated matrix factorization algorithm, to turn rolling correlation and tail-dependence matrices into hard clusters, soft factor...

Use AdaptGrow, a GPU-accelerated matrix factorization algorithm, to turn rolling correlation and tail-dependence matrices into hard clusters, soft factor loadings, and structural-break signals at single-GPU and multi-node scale Quant strategies routinely group instruments for portfolio construction, risk aggregation, statistical arbitrage, and trade surveillance. Incorrect groupings can make…

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AI agents are only as effective as the context they receive. Even with capable models and well-documented NVIDIA libraries, agents can spend extra steps finding...

AI agents are only as effective as the context they receive. Even with capable models and well-documented NVIDIA libraries, agents can spend extra steps finding the right tools, burn tokens on dead ends, or struggle with specialized tasks. Skills package the instructions, examples, and tool guidance for agents to move faster from intent to solution. To measure whether these skills improve agent…

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Robots need policies that can adapt to their sensors, environments, and tasks while running on onboard computing hardware. World models offer a foundation for...

Robots need policies that can adapt to their sensors, environments, and tasks while running on onboard computing hardware. World models offer a foundation for learning physical interactions, but their size can make on-device deployment difficult. This changes with the new NVIDIA Cosmos 3 Edge. Cosmos 3 Edge is a 4B omni-model (with a 2B NVIDIA Nemotron-based reasoner) in the Cosmos 3 family.

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Atomistic simulation requires three things: knowledge of the science, compute-efficient implementation of simulations, and accessible interfaces to the...

Atomistic simulation requires three things: knowledge of the science, compute-efficient implementation of simulations, and accessible interfaces to the simulation stack. The first remains the researcher’s domain, as no tool substitutes for knowing what to simulate or recognizing a physically meaningful result. NVIDIA ALCHEMI Toolkit, introduced earlier this year, has dramatically reduced the…

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Uniform Manifold Approximation and Projection (UMAP) is a dimensionality reduction technique widely used for visualization and feature extraction. Applications...

Uniform Manifold Approximation and Projection (UMAP) is a dimensionality reduction technique widely used for visualization and feature extraction. Applications range across exploratory data analysis, topic modeling, and single-cell analysis. Many of these workflows are iterative and exploratory, requiring UMAP to be run repeatedly as users analyze their data or tune parameters. As datasets grow…

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A central challenge in robotics is building policies that generalize beyond the demonstrations they’re trained on. A policy that succeeds in a training scene...

A central challenge in robotics is building policies that generalize beyond the demonstrations they’re trained on. A policy that succeeds in a training scene often fails when object shapes, positions, or lighting change. Generalizing to these new conditions requires the policy to understand the tasks underlying physics, not just mimic the demonstrations. This ability comes from the backbone it’s…

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Autonomous vehicle (AV) development often relies on separate models for trajectory generation, high-level intent prediction, scene understanding, and data...

Autonomous vehicle (AV) development often relies on separate models for trajectory generation, high-level intent prediction, scene understanding, and data labeling. This separation makes it hard to compare related outputs, investigate model behavior, and reuse the same representations across the development workflow. NVIDIA Alpamayo 2 Super is an open 34-billion-parameter reasoning vision…

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Unlike autonomous driving or industrial robotics, healthcare robotics can’t rely on internet-scale data collection or unlimited real-world experimentation....

Unlike autonomous driving or industrial robotics, healthcare robotics can’t rely on internet-scale data collection or unlimited real-world experimentation. Every demonstration requires specialized equipment, clinical expertise, and access to patients or laboratory environments. This creates three fundamental challenges for developers. First is the data gap. Training modern robotic policies…

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NVIDIA Ising Calibration is an open source vision language model (VLM) designed to interpret diagnostic outputs from quantum processors and determine how they...

NVIDIA Ising Calibration is an open source vision language model (VLM) designed to interpret diagnostic outputs from quantum processors and determine how they should be tuned to continue operating. This post introduces the latest model release, NVIDIA Ising Calibration 1.5, which advances AI-based QPU calibration by analyzing unfamiliar diagnostic results without prior training examples.

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As AI workloads increase, explosive compute demand is pushing the semiconductor industry to meet unprecedented performance targets. Even small delays can have...

As AI workloads increase, explosive compute demand is pushing the semiconductor industry to meet unprecedented performance targets. Even small delays can have outsized financial impact in fast-moving AI hardware cycles. Simultaneously, the shift from chip-level optimization to system-level engineering is compounding thermal and power challenges. Meeting these demands requires breakthroughs…

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Developers building 3D, design, simulation, robotics, and industrial digital twin applications need ways to bring physical AI capabilities into the tools and...

Developers building 3D, design, simulation, robotics, and industrial digital twin applications need ways to bring physical AI capabilities into the tools and services they already use. Many of these workflows already depend on OpenUSD scenes, simulation-ready (SimReady) assets, Blender-based workflows, CAD pipelines, or domain-specific app stacks. The challenge is how to provide applications and…

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OpenUSD is an open, extensible framework that provides a common scene description language for physical AI. It enables teams to bring CAD data, simulation...

OpenUSD is an open, extensible framework that provides a common scene description language for physical AI. It enables teams to bring CAD data, simulation assets, and real-world telemetry into a shared, physically accurate view of the world. Until now, building a USD implementation has typically required adapting a large existing codebase— even for teams that need a specific memory footprint…

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What if autonomous coding AI agents could push your vision reasoning models above 90% accuracy with almost no manual effort? When adapting vision reasoning...

What if autonomous coding AI agents could push your vision reasoning models above 90% accuracy with almost no manual effort? When adapting vision reasoning models to production video tasks, developers often lose days to data formatting, container setup, training scripts, baseline evaluation, and hyperparameter sweeps before they even know whether post-training improves accuracy.

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Across science, engineering, and finance, many of the most important risks come from low-likelihood, high-impact events. Estimating the probability of these...

Across science, engineering, and finance, many of the most important risks come from low-likelihood, high-impact events. Estimating the probability of these events with brute-force Monte Carlo sampling—running a model repeatedly with randomly drawn inputs to estimate the probability of rare outcomes—can require an excessive volume of model iterations, especially when each sample comes from an…

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Large language model (LLM) training workloads increasingly run into GPU memory limits before compute is fully used. Model weights, gradients, optimizer states,...

Large language model (LLM) training workloads increasingly run into GPU memory limits before compute is fully used. Model weights, gradients, optimizer states, communication buffers, and intermediate activations all compete for GPU high-bandwidth memory (HBM). As model size, sequence length, and batch size grow, HBM capacity often becomes the primary scaling bottleneck. This post explains how…

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