Across major economies, trustworthy artificial intelligence is rapidly moving from high-level policy to deployment in core industries such as health, manufacturing and mobility. The European Union is positioning itself for this shift by focusing not only on innovation capacity but also on trustworthy and coordinated implementation across its Member States. Gaining a deeper understanding of where AI is already being applied and gathering evidence on determinants of adoption are essential to assess Europe’s competitiveness and policy readiness.

The European Union is pursuing its ambition to become a global leader in trustworthy AI, moving from high-level policy to on-the-ground implementation. The OECD worked closely with the European AI Office to monitor efforts to develop trustworthy AI and promote its development across the European economy, with a two-volume publication series analysing how this transition is taking place in practice. The first volume focuses primarily on national strategies, initiatives and governance mechanisms for AI in EU Member States. The second, Progress in Implementing the European Union Coordinated Plan on Artificial Intelligence (Volume 2), shifts the lens to sector-specific impact.

The report supports efforts by the European Commission and EU Member States to promote the development, deployment, and use of AI technologies across priority sectors. It draws on extensive multi-stakeholder engagement, including semi-structured interviews with industry experts and insights from dedicated stakeholder workshops. It focuses on concrete use cases that address specific needs in agriculture, healthcare, manufacturing and mobility, selected high-impact sectors where AI can contribute to digitalisation, sustainability and economic resilience. These sectors are most prominently featured across national AI strategies (Figure 1) as priority sectors for AI applications.

Agriculture: from precision to sustainability

Globally, agricultural producers are increasingly turning to AI-enabled precision tools to address labour shortages, environmental pressures and resource constraints. Within Europe, similar dynamics are shaping experimentation with AI-supported farming systems aligned with environmental targets under the European Green Deal.

As AI-driven solutions help optimise resources, reduce chemical inputs and maintain yields, the EU’s agricultural sector is exploring AI deployment to address structural workforce shortages and sustainability requirements. AI-powered agricultural robots and crop and soil monitoring systems are playing a growing role in improving resource efficiency.

Robs4Crops, for instance, illustrates how computer vision and sensor-based systems can enable autonomous mechanical weeding and spraying in vineyards, crop fields and apple orchards. AI4SoilHealth, in turn, is developing an open-access, AI-driven digital infrastructure to help assess and monitor soil health metrics across Europe.

At the same time, many initiatives remain at pilot or experimental stages. Limited digital infrastructure in rural areas, fragmented and inaccessible datasets (due to the resources required to collect high-quality, diverse data across crops, soil, and livestock, and to limited interoperability of existing public datasets), financial barriers, and uncertainty over return on investment continue to constrain large-scale adoption.

Healthcare: enhancing diagnostics and operations

Health systems worldwide are using AI to improve diagnostic accuracy and manage increasing service demand. In Europe, demographic ageing and workforce shortages are strengthening the case for deploying AI across both clinical and operational settings.

AI can help address rising costs and workforce shortages in healthcare while improving patient outcomes through faster and more accurate diagnostics.

One of the most impactful use cases is AI-enhanced medical imaging for the early detection of conditions such as cancer, supported by initiatives including the European Cancer Imaging Initiative. Similar approaches are already being deployed in the United States and Japan, where AI-assisted radiology is helping reduce diagnostic backlogs, highlighting the strategic importance of scaling comparable capabilities across Europe.

Beyond clinical care, the report explores how AI is improving hospital operations. Predictive and optimisation AI systems can help forecast patient inflows and manage bed occupancy, helping healthcare providers reduce staff pressure and waiting times. Perplex, an EU-funded initiative, illustrates how AI can help automate and optimise scheduling and resource management in the outpatient department of a hospital in Madrid.

Despite this potential, barriers such as fragmented health data environments and trust challenges remain significant constraints.

Manufacturing: the rise of industrial intelligence

Competitiveness in the manufacturing sector increasingly depends on integrating AI into production systems, supply chains, and quality control processes. While other major economies are accelerating investment in smart factories, adoption across Europe remains uneven.

AI adoption in EU manufacturing remains modest and highly fragmented, with pharmaceuticals and electronics leading the way, while traditional industries such as textiles and food processing progress more slowly.

Despite these differences, there are areas where AI could have a substantial impact. The report highlights three priority use cases: predictive maintenance, quality assurance and control, and supply chain optimisation.

Predictive maintenance systems, such as those developed through the Made in Europe Partnership, analyse sensor data to forecast equipment failures and reduce costly downtime. In quality control, AI-powered inspection improves efficiency by identifying defects in real time. Comparable smart-manufacturing deployments in East Asia and the United States demonstrate how scaling such applications can strengthen productivity growth and industrial resilience.

Mobility: navigating toward a connected future

Transport systems are becoming increasingly data-driven as cities and logistics operators deploy AI to improve safety, efficiency and sustainability. Across Europe, mobility-sector deployment is closely linked to broader digital and climate transition strategies.

AI can help transport and mobility systems become safer, more efficient and more sustainable. AI-enabled traffic management systems, such as those explored in the AI4Cities project, can reduce congestion by dynamically adjusting traffic-light patterns. Automated driving technologies and intelligent freight logistics systems can further optimise routes and scheduling efficiency. Here, the EU Connected, Cooperative and Automated Mobility (CCAM) Partnership aims to accelerate the transition from research prototypes to real-world applications.

These developments are intended to align with the Sustainable and Smart Mobility Strategy, although gaps in infrastructure readiness and investment capacity remain important constraints for many operators.

Overcoming barriers to scale

Progress in Implementing the European Union Coordinated Plan on Artificial Intelligence (Volume 2) demonstrates significant sectoral potential for AI deployment, while identifying persistent bottlenecks that continue to slow implementation. Addressing these constraints will be critical to moving from experimentation with pilots to widespread deployment that fundamentally transforms the European economy for the better. To do so, the report puts forward a number of key recommendations, including the following:

• Focus on concrete sector-specific AI use cases

Targeted policies, investment, and collaboration will be essential to unlock AI’s full potential in key sectors of the EU’s economy. Public-private-academic partnerships, open innovation platforms, and cross-border collaborations can accelerate AI development and adoption, particularly when grounded in sector-specific needs. Focusing on concrete AI use cases, building ownership and trust through transparency and co-design with end-users, and demonstrating tangible benefits will be key to ensuring that AI strengthens Europe’s economic competitiveness, sustainability, and societal well-being.

• Strengthen data foundations

Investing in high-quality datasets, common standards and shared governance frameworks can enable secure, privacy-preserving data sharing across borders and sectors. Improving data representativeness and reducing fragmentation will lower entry barriers and support downstream AI adoption.

• Expand infrastructure and compute capacity
  Investments in broadband connectivity, cloud and edge computing, 5G networks and AI compute environments—including AI factories and high-performance computing centres—are essential to bridging regional gaps. Initiatives such as EuroHPC are helping ensure that economic actors, including SMEs, can access the computational resources required to train and deploy advanced AI models.

• Close the skills and talent gap
  Unlike their larger counterparts, who tend to have more resources at their disposal, smaller firms and public organisations require access to technical expertise and sector-specific training before large-scale deployment of AI becomes feasible. European Digital Innovation Hubs (EDIHs) are supporting this process through a “test before invest” approach that lowers adoption risks.

• Enhance trust and regulatory coordination
  Regulatory sandboxes allow firms to test innovative AI applications under supervisory conditions, enabling regulatory learning and improving compliance readiness before market entry. Providing clearer guidance and harmonising regulatory interpretation across Member States will remain particularly important for start-ups and SMEs operating under the EU AI Act, alongside relevant existing rules such as the GDPR.

Many of the report’s findings align with the European Commission’s Apply AI Strategy, which focuses strongly on accelerating adoption and the active deployment of AI across the economy. The OECD and the European Commission will continue working together to support implementation of the Strategy and to ensure that lessons from European AI deployment experiences contribute to the broader global AI policy community.

The authors would like to thank John Leo Tarver for his contributions to this report series and blog posts.

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AI agents and agentic AI based on large language models are becoming more autonomous and capable of interacting with both physical and virtual environments. As the capabilities of these AI systems grow, they are gaining visibility, and with reason. It is reaching a point where they could become the driving force behind innovation, investment and improved productivity across sectors by streamlining processes and enabling more efficient operations.

While ideas related to agency have long been explored in academic research in fields such as philosophy, economics and computer science, recent advances in AI are stretching conceptual boundaries. As AI’s capabilities evolve, so do our shared understanding of what qualifies as AI agent and agentic AI.

The OECD report, The agentic AI landscape and its conceptual foundations, developed by the OECD.AI Expert Group on Agentic AI, helps clarify what AI agents and agentic AI are and how they differ. Grounded in the OECD AI system definition, the analysis examines how these terms are defined and used across the literature. By analysing key features, overlaps and distinctions and mapping them to the core elements of the OECD definition of an AI system, the report helps to establish more precise and consistent terminology. And in a rapidly evolving field, conceptual precision is essential for effective, well-informed governance.

Three key messages stand out in the report:

• AI agents and agentic AI are closely related, but not interchangeable.
• Agentic AI ought to be seen as a socio-technical paradigm.
• Despite technological gaps and varying levels of maturity in areas such as digital security and privacy, uptake is growing.

The common foundations and meaningful distinctions of AI agents and agentic AI

Our analysis shows that AI agents and agentic AI share foundational characteristics. Both involve systems with a degree of autonomy that pursue goals and can perceive and act within physical and virtual environments.

However, there are differences that mean these terms are not interchangeable.

1. AI agents can be understood as systems that perceive and act on their environment with a degree of autonomy, using tools as needed to achieve specific goals and adapt to changing inputs and contexts.
2. By contrast, agentic AI generally refers to systems composed of multiple co-ordinated AI agents that can break down tasks, collaborate and pursue complex objectives autonomously over extended periods. Agentic AI systems are designed to operate in more open-ended, less predictable physical and virtual environments, and to function with minimal human supervision.

In short, agentic AI is more complex, as it can co-ordinate multiple agents, perform task decomposition and delegation, and sustain operations over longer periods. It can also operate in more complex, less predictable environments with limited human oversight.

Agentic AI as a socio-technical paradigm

Agentic AI systems are not isolated technical artefacts. They are frequently embedded in social contexts and interactions and operate within a socio-technical paradigm.

Their value lies not only in autonomous action, but in interaction with other AI agents, humans and institutional processes. Co-ordination and negotiation across these actors require advanced reasoning capabilities, robust infrastructure and reliable communication protocols.

This relational perspective is an essential part of what agentic AI is. This means that understanding how they interact within broader ecosystems is essential to designing agentic AI systems that function responsibly and effectively, particularly in open or high-stakes environments.

Uptake is accelerating, but maturity is uneven

The report also presents descriptive evidence on trends in AI agent adoption. Many developers have already integrated them into their toolkits, and survey data indicate that nearly half of respondents on Stack Overflow use them or plan to do so.

To be clear, adoption should not be confused with maturity. Developers highlight opportunities to further strengthen the security, privacy and accuracy of AI agents. These concerns underscore an important point: as the capabilities of agentic AI advance rapidly, progress in robust, trustworthy AI systems must keep pace.

A foundation for further analysis

Overall, the report provides a descriptive overview of the agentic AI landscape, clarifying key concepts and characteristics and establishing a shared analytical foundation. By anchoring the discussion in the OECD AI system definition, it aims to promote coherence across technical and policy communities.

Looking ahead, an improved understanding of real-world use will be essential to identify where safeguards, standards, and governance mechanisms will be most effective. Policy-relevant typologies that build upon this work could help guide governance efforts to distinguish systems by level of autonomy, degree of adaptiveness, domain of operation and scale of impact. Evidence-based policymaking will require more empirical data on how AI agents and agentic AI are being adopted and used across sectors, as well as clearer evidence of their broader implications and impacts.

This report contributes to a clearer, shared understanding of agentic AI and provides a basis for thoughtful, forward-looking policy grounded in conceptual clarity. As agentic AI systems become more capable of coordinating multiple AI agents, taking action and operating over longer periods, governance conversations have to keep pace.

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Companies hoping to take advantage of AI’s opportunities need to be trustworthy. Whether investing in, developing, or using AI, the OECD’s new Due Diligence Guidance for Responsible AI provides businesses with an internationally agreed, government-backed tool to demonstrate that markets and societies can trust their AI systems.   

Recent international reporting underscores a growing consensus: AI is not just a technological shift. It is a major geopolitical, economic, and societal phenomenon that demands coordinated action amongst all actors, including companies. 

AI has the potential to transform society through productivity, economic value and solutions to complex challenges, but for these benefits to materialise, AI needs trust.  So far, the technology seems to advance faster than its guardrails. The gap between AI systems and appropriate safeguards is now one of the defining challenges for policymakers and global businesses alike. Both are under pressure to balance AI innovation and diffusion with safety and risk management. Success depends on getting the balance right.

Risks throughout the AI value chain are continually evolving

Risks to people and the environment can manifest at any point along the AI value chain. The OECD actively tracks and categorises risks through its AI Incidents and Hazards Monitor.

Here are a few examples. At one end of the AI value chain, there are the people who label, clean, and moderate the vast datasets required to train AI models. They can face low wages, long hours, and suffer psychological distress from exposure to harmful content. Companies need to ensure decent work for data enrichment workers.

The environmental costs of running AI systems can also be significant, particularly for energy and water consumption by data centres that power AI development and deployment, which may lead to higher energy prices.

Data privacy is another critical concern. AI models are trained on massive datasets that may include personal or sensitive information. If these datasets are not properly anonymised and secured, it can lead to data breaches. If AI models “memorise” and reproduce sensitive data in their outputs, they can expose confidential details, creating legal and ethical dilemmas.

At the other end of the AI value chain, the potential for AI misuse poses risks such as reputational harm and the spread of misinformation. AI-generated deepfakes, for instance, can be used to create realistic but fabricated content, damaging reputations or manipulating public opinion. Similarly, AI can be used to generate and disseminate mis and dis-information at speed and scale, eroding trust in institutions and potentially influencing events.

Worldwide, governments, consumers, and markets are calling for responsible and trustworthy AI. This is one of the reasons for the surge in mandatory and voluntary AI risk management frameworks, responsible AI initiatives, global agreements, academic research and statements from industry leaders and investors. However, this surge in frameworks is also increasing complexity for companies, as risk management is defined differently across jurisdictions and understanding of AI-related risks is evolving.

OECD Due Diligence Guidance for Responsible AI: A flexible, whole-of-value-chain approach to support businesses in navigating evolving risks and rules

This is why the OECD has now developed the first internationally agreed, government-backed Due Diligence Guidance for Responsible AI. Backed by all the OECD’s member countries, plus 17 partner governments and the EU, this Guidance helps enterprises navigate the complex terrain of AI risk management. It is designed to help businesses ensure that the AI systems they develop are trustworthy, used and developed safely and responsibly, and aligned with broad societal values.

Concretely, this Guidance offers:

• A step-by-step framework for enterprises to set up internal management systems capable of proactively identifying and responding to risks related to human rights, labour standards, and environmental impacts.
• Comprehensive coverage of all risk areas from the leading international standards that it is built on and reflects, notably, the OECD Guidelines for Multinational Enterprises on Responsible Business Conduct (MNE Guidelines) and the OECD Recommendation on Artificial Intelligence (AI Principles);
• Recommendations and implementation examples for everyone in the AI value chain, from data suppliers and infrastructure providers to financiers and end-users – including enterprises. The guidance emphasises a “whole-of-value-chain” approach to support secure and resilient AI value chains more resistant to supply chain shocks and interference.
• A roadmap of related provisions in existing frameworks, indicating how each step complements and relates to relevant provisions from AI risk management frameworks. This feature helps enterprises understand how implementing this guidance can help them meet expectations from multiple sources and navigate the current landscape of AI risk management frameworks.

Responsibility and trust can give a competitive edge

Responsibility and innovation not only coexist but also reinforce each other. Companies that show a commitment to responsible AI and actively address potential risks can gain trust from investors, customers, regulators, and policymakers. This trust leads to a competitive edge. Instead of hindering innovation, responsible AI practices can speed up growth by reducing obstacles and preventing costly damage to reputation, legal issues, and society.

Responsible and trustworthy AI is becoming increasingly crucial for accessing global markets as international regulatory and voluntary risk management frameworks evolve. Companies in the AI value chain that meaningfully implement the Guidance’s recommendations can position themselves advantageously for cross-border expansion, potentially avoiding the substantial costs of retrofitting systems to meet various regional requirements.

As AI continues to develop rapidly, frameworks and best practices for responsible AI are likely to evolve as well. To help stakeholders keep pace, the OECD will launch an online navigation tool later this year with updates on new frameworks and use cases.

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