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High-Throughput Structure Prediction with BioNeMo Inference Runtime

10 September 2026 at 15:00
Biomolecular structure prediction is now often run at proteome scale, where the goal is to move an entire worklist through the pipeline efficiently. NVIDIA...

Biomolecular structure prediction is now often run at proteome scale, where the goal is to move an entire worklist through the pipeline efficiently. NVIDIA BioNeMo Inference Runtime (BioIR) helps accelerate supported biomolecular structure-prediction models on NVIDIA GPUs while keeping the familiar PyTorch workflow. It uses optimized kernels and, where applicable, CUDA Graphs to speed model…

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Frontier Reasoning Reaches the Edge: How to Deploy and Optimize Models on NVIDIA Jetson

4 September 2026 at 16:21
Running reasoning and agentic AI at the edge has been harder than it needs to be. Until recently, models capable of multi-step reasoning were too large to run...

Running reasoning and agentic AI at the edge has been harder than it needs to be. Until recently, models capable of multi-step reasoning were too large to run locally on edge hardware. Developers building agents have had to route inference through a data center, adding network dependency, increasing costs, and exposing data that may need to stay on device. That constraint is lifting.

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NVIDIA PAIR Virtual Inference Router Expands Available Compute on Your Local Network

3 September 2026 at 16:00
AI agents are learning to do more by working together. A lead agent can break a complex task into smaller jobs and assign those jobs to specialized subagents....

AI agents are learning to do more by working together. A lead agent can break a complex task into smaller jobs and assign those jobs to specialized subagents. Additionally, users are starting to run multiple agent sessions at the same time. Multi-agent workflows for accomplishing complex tasks are also becoming more common. This breadth-first approach can improve the speed of task completion…

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SpaceX designed an orbital Vera Rubin. Radiation comes next.

NVIDIA Vera CPU

SpaceX and Nvidia say they are adapting the Vera Rubin NVL72 rack-scale AI platform for orbital use, with SpaceX targeting a first launch in the fourth quarter of 2027. 

The dream of an AI data center in space lives on in SpaceX and Nvidia’s August 24 announcements that the platform for Low Earth Orbit (LEO) Starmind AI satellites will be based on the Vera Rubin NVL72 chip family and architecture.

This proposed system would form the computing core of SpaceXAI’s first-generation Starmind AI satellite and extend Nvidia’s architecture from terrestrial AI data centers into space. 

SpaceX CEO Elon Musk posted on X the same day, “SpaceX, in partnership with Nvidia, has designed a space-optimized Vera Rubin NVL72 system for launch to orbit in Q4 next year, with significant scale in 2028.”

SpaceX, in partnership with Nvidia, has designed a space-optimized Vera Rubin NVL72 system for launch to orbit in Q4 next year, with significant scale in 2028 https://t.co/qdDq8YBkzl

— Elon Musk (@elonmusk) August 24, 2026

Musk’s post came after he said during SpaceX’s Q2 earnings call, “Going forward, we’ve decided to build exclusively on Nvidia because we think the Vera Rubin architecture is the best architecture.” Musk continued, “This is not some sort of far-future, distant thing; we expect to start launching these next year. We think the design of the NVL72 VR computer is a much better design than, say, having a standard rack -style design. So we expect to deploy this on the ground as well as in orbit, because we think it’s going to be a radical simplification of the standard NVL72 rack. It will cost less. It will be more effective. If we’re going to put it in space, why not want to put it on the ground? I think that’s going to be pretty cool.”

On Earth, the Vera Rubin NVL72 is Nvidia’s rack-scale AI design that combines 72 Rubin GPUs and 36 Vera CPUs, alongside high-speed networking components such as ConnectX-9 SuperNICs. Nvidia says SpaceXAI’s planned Starmind satellite will be based on an optimized version of that system.

A conventional NVL72 rack assumes gravity, technicians, stable grid power, a building-scale liquid loop and frequent replacement of failed parts. Orbit removes each of these assumptions.

The idea is more ambitious than putting a conventional edge-AI accelerator aboard a spacecraft. Nvidia and SpaceXAI are proposing to bring a modified architecture used in AI data centers into orbit, while altering it for orbital operational requirements.

Getting that working in orbit, though, is easier said than done. 

As Curtis Pyke, founder of Kingy AI, writes, “A conventional NVL72 rack assumes gravity, technicians, stable grid power, a building-scale liquid loop and frequent replacement of failed parts. Orbit removes each of these assumptions.

“Cooling is unforgiving. Space is cold, but vacuum does not carry heat away through convection.”

In particular, Pyke continues, “Cooling is unforgiving. Space is cold, but vacuum does not carry heat away through convection. Heat must travel from the chips to the radiator surfaces and then leave as infrared radiation. SpaceX says AI1 can avoid chillers, cooling towers and fans and reduce cooling overhead by an order of magnitude.”

SpaceX explains that AI1 would instead use closed-loop liquid cooling inside the spacecraft and large deployable radiators to send heat directly to space as infrared radiation. While the claimed reduction is physically plausible in principle, there’s no proof yet that these AI satellites’ cooling systems can deliver. 

Another major problem that remains unaddressed is how to make the orbital rack radiation-tolerant. Making Vera Rubin NVL72 radiation-tolerant means far more than putting an ordinary NVL72 rack in a shielded satellite enclosure. It would require a system-level redesign of its GPUs, CPUs, memory, networking, power, cooling, firmware, and operations around a specified orbit and mission life.

LEO orbit is not benign. NASA cites typical trapped-particle dose rates of 100 to 1,000 rad(Si) per year for low-inclination LEO spacecraft below 500 km. That level of radiation is not an immediate death sentence for electronics, but over a multiyear mission it will cause cumulative degradation. Radiation-qualified space hardware can deal with that. Commercial Off-The-Shelf (COTS) electronics are another matter. A true radiation-hardened Rubin GPU would also require design changes at the transistor and circuit levels. 

Even were Nvidia to make such a chip, for a high-density AI system such as the SpaceX design, the concern isn’t simply whether one processor survives a 5- or 10-year dose. The satellite contains numerous radiation-sensitive elements, such as GPU logic, SRAM caches, register files, system memory, and memory controllers. With thousands of cores and billions of memory storage cells, the aggregate fault rate — not the behavior of an individual component — drives the design.

The most realistic near-term answer would be a radiation-tolerant, fault-managed Rubin-derived orbital system, not a fully radiation-hardened NVL72 in the traditional military-space sense. It could use selected commercial Nvidia parts, substantial shielding, ECC and data integrity mechanisms, redundant controllers and power paths, aggressive fault detection, software recovery, and reduced-performance operating modes.

The post SpaceX designed an orbital Vera Rubin. Radiation comes next. appeared first on The New Stack.

Deploy an Open Model from Checkpoint to Inference in Two Commands with NVIDIA TensorRT Model Connect

28 August 2026 at 17:06
Open AI models are evolving faster than ever, but bringing them into native applications can still require model-specific conversion, preprocessing,...

Open AI models are evolving faster than ever, but bringing them into native applications can still require model-specific conversion, preprocessing, post-processing, and runtime code. NVIDIA TensorRT Model Connect open collection of reference implementations helps to address this challenge. TensorRT Model Connect shows you how to run supported models with NVIDIA TensorRT in native C++…

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Kodiak AI and AMD collaborate to advance computing power for driverless trucking

27 August 2026 at 13:02
Kodiak AI, a provider of physical AI-powered autonomous driving technology, has announced a collaboration with chipmaker AMD to implement its AMD EPYC Series processors to power Kodiak’s seventh-generation autonomous truck platform. Kodiak is the first company to deploy the advanced AMD EPYC processors into their hardware platform for driverless trucking. High-performance AMD EPYC Series CPUs […]

NFTs vs Traditional Art Sales: Opportunities and Challenges

21 August 2026 at 10:25
Artists have sold their work through galleries, art fairs and auction houses to collectors worldwide for centuries: walk in, look at a piece and pay for something to hang on a wall. NFTs changed that. Now an artist can sell a digital file directly to a buyer anywhere in the world, with a blockchain tracking […]

Waymo reveals Nvidia-powered compute system behind its robotaxis

21 August 2026 at 08:48
Waymo has revealed new technical details about the onboard computing system that powers its autonomous driving technology, including a purpose-built 5 nm ASIC delivering more than 1,000 TOPS of machine learning performance. The company says its latest compute architecture is designed to provide millisecond-level response times while operating under the vibration, temperature extremes and other […]

Developing NVIDIA Holoscan Applications with CLI, Skills, and AI Coding Agents

19 August 2026 at 22:22
NVIDIA Holoscan is a platform for building real-time AI applications at the edge, from medical imaging to robotics. HoloHub is its companion repository: a...

NVIDIA Holoscan is a platform for building real-time AI applications at the edge, from medical imaging to robotics. HoloHub is its companion repository: a growing collection of reference applications and components that demonstrate what’s possible. We wanted to explore how a general-purpose coding agent could use the same examples, documentation, and development tools available to an engineer…

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Building Federated Multimodal AI Workflows with NVIDIA FLARE

19 August 2026 at 17:50
Modern vision-language models (VLMs) can support tasks such as visual question answering, captioning, and image-text reasoning. In practice, however, the data...

Modern vision-language models (VLMs) can support tasks such as visual question answering, captioning, and image-text reasoning. In practice, however, the data needed to adapt these models may be distributed across institutions or organizations that cannot centralize their raw records. Federated learning provides a way to coordinate training across these data-local sites. For VLMs…

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Post-Train NVIDIA Cosmos 3 Edge for On-Device Robot Control

19 August 2026 at 16:00
A robot picking up a tool.Robots need policies that can adapt to their sensors, environments, and tasks while running on onboard computing hardware. World models offer a foundation for...A robot picking up a tool.

Robots need policies that can adapt to their sensors, environments, and tasks while running on onboard computing hardware. World models offer a foundation for learning physical interactions, but their size can make on-device deployment difficult. This changes with the new NVIDIA Cosmos 3 Edge. Cosmos 3 Edge is a 4B omni-model (with a 2B NVIDIA Nemotron-based reasoner) in the Cosmos 3 family.

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Hexagon starts training AEON humanoid robots at Schaeffler factories

19 August 2026 at 10:32
Hexagon Robotics and Schaeffler, a motion technology company, has announced the next milestone in their strategic collaboration as AEON enters Schaeffler’s Humanoid Gym in Germany, marking the next step towards the planned deployment of at least 1,000 AEON humanoids in the coming years. The Humanoid Gym provides a Train-Validate-Deploy model in a dedicated industrial environment. Schaeffler […]

Agentic AI has a latency problem that more compute won’t solve

Abstract neon pattern of distorted purple columns and lime-green rings rippling across a dark background.

Half of enterprise AI deployments are missing their own latency targets at peak load. This is the headline finding of Akamai’s State of AI Inference 2026 report, which surveyed 200 AI practitioners and found that 82% of organizations say their most critical use cases require end-to-end response times of 500 milliseconds or less. A total of 64% of organizations now require end-to-end response times of less than 250 milliseconds for their most important use cases, yet 50% of deployments are failing to meet these latency demands at peak load.

My colleague Ari Weil, who leads product marketing for our cloud computing business and ran point on that research, summarizes the findings well: “The enterprise AI honeymoon phase is over… they are hitting the latency wall.” 

Agentic workflows aren’t a “single round trip”

The latency issue stems from the way agents work. It’s an iterative process, somewhat like a king sending out knights, emissaries, and messengers to conduct the business of the kingdom. There are many comings and goings, not just one person sent on a single round trip. 

For instance, when an agent built on a framework like LangChain, CrewAI, or Pydantic AI received a user request, it can fan out into dozens of sequential operations such as a reasoning call, a tool invocation, an API lookup, or a context retrieval. Then an agent may execute another reasoning call to decide what to do with what just came back. Every one of these operations or “hops” that must cross a wide-area network to reach a centralized data center adds latency, and a chain of 50 hops can multiply that transport time into seconds on its own, regardless of how fast the model generates tokens.

In fact, in a paper posted to arXiv in November 2025, researchers found that CPU-side processing can account for up to 90.6% of total latency in agentic workloads. In other words, your GPU might finish a reasoning step in a few hundred milliseconds, but then it might have to wait on additional tool call runs to CPUs in distant data centers. This is what causes spikes in GPU idle time. 

“More GPU capacity does nothing for this. You can’t brute-force your way out of a wait state.”

More GPU capacity does nothing for this. You can’t brute-force your way out of a wait state. This is the part of the conversation the industry keeps skipping, mostly because “buy more GPUs” is a much quicker fix to suggest than “figure out where your CPU-bound work is actually executing and why it’s so far from the data it needs.”

We need new benchmarks to fix the latency issue

One reason the looming latency wall sneaks up on teams is that they are not looking at the right benchmarks for agentic workloads. Most LLM-serving benchmarks measure tokens per second and GPU utilization on a single box. That’s great if the workload is indeed on a single box (i.e., one model answering one prompt), but that’s not the case with agentic workloads. Those benchmarks don’t address an agentic response that, say, makes a 50-hop chain cross a WAN 4 times to reach 4 separate services. 

“Staging may pass the benchmarks because it tests the model, but production tests the whole chain, including every hop your serving engine was never designed to see.”

That’s where the gap lies: Staging may pass the benchmarks because it tests the model, but production tests the whole chain, including every hop your serving engine was never designed to see.

The 500ms wall is not a soft target

This is showing up at scale because agents are moving into production faster than most teams’ architecture is evolving to support them. LangChain’s State of Agent Engineering 2026 survey of more than 1,300 professionals found that 57.3% of organizations now have agents running in production, up from 51% a year earlier. Among those builders, latency has become the second-most-cited barrier to production, behind only output quality. 

This is a serious issue for application teams. The 500ms threshold in Akamai’s survey isn’t a performance goal teams can afford to miss. For a live customer interaction or a real-time compliance check, that 500ms determines whether the application works or it doesn’t. 

We’ve solved this problem before

There’s a reason this feels familiar to anyone who was building for the web in 1999. Akamai exists because of a nearly identical problem. MIT researchers Tom Leighton and Danny Lewin founded the company to answer a challenge posed by Tim Berners-Lee: fix what the press had started calling the “World Wide Wait,” the crushing latency of pulling every request back to a small number of centralized servers. When the trailer for The Phantom Menace crashed sites across the internet in 1999, the culprit was distance: millions of browsers all reaching for the same far-away origin server at the same moment. The fix moved content to thousands of points closer to the people requesting it, instead of trying to build a faster origin.

Agentic AI is running into the same wall, just in a different vehicle. AI works just fine on centralized inference if you’re talking about running batch jobs overnight. But today’s applications built on agentic AI are real-time loops sitting inside live transactions, and the fix for agentic lag is distribution. Instead of expanding racks of CPUs and GPUs at the center, we need to move agentic execution to where the model’s tools, context data, and users actually live.

Agentic AI needs a tiered architecture, not a bigger data center

In practice, agentic AI requires a tiered architecture, one that includes a centralized core, regional GPU clusters, and CPUs at the Edge. 

  • Centralized core—perfect for heavy reasoning over large context windows, where the round trip to a large model matters less than the model’s raw capability.
  • Regional GPU clusters, increasingly built on hardware like NVIDIA’s Blackwell platform—ideal for localized inference, so the heaviest compute sits closer to where demand actually concentrates.
  • Edge CPUs—the essential component for speed. This is the nexus for tool execution, orchestration, and context retrieval, since these are the steps that happen most often in a chain and benefit most from sitting next to the data and APIs they call.

We’ve built Akamai Inference Cloud around this tiered framework. It’s the same distribution logic behind our AI Grid Orchestrator. We route CPU-bound orchestration and tool calling to the edge, and keep GPU-bound reasoning where it makes sense, regionally or centrally. 

What to demand before you commit

The good news is you don’t need to distribute every workload to the edge on day one. But before you commit to a production architecture, you should know which of your agent’s dozens of hops are latency-sensitive and which aren’t. Then build a defined performance budget for each one.

“The teams that treat it as a GPU-shopping decision will be back here in six months, staring at the same four-second response time, wondering why more compute didn’t help.”

My advice is this: Before signing off on a large-scale inference deployment, ask your infrastructure for four things: 

  1. Portability across regions and providers
  2. Elasticity to absorb peak load without falling over
  3. Data locality so tool calls aren’t crossing oceans to reach the context they need
  4. A performance budget you’ve actually tested against production traffic, not staging traffic.

The teams that address this infrastructure decision now will be the ones whose agents still work when the benchmark environment transitions to real users. The teams that treat it as a GPU-shopping decision will be back here in six months, staring at the same four-second response time, wondering why more compute didn’t help.

The post Agentic AI has a latency problem that more compute won’t solve appeared first on The New Stack.

Developing Nemotron 3.5 Lightning NVFP4 with QAD Using NVIDIA Model Optimizer

17 August 2026 at 18:12
Teams customize their models to hit their targets for latency, speed, memory, and compute. With the open NVIDIA Nemotron family of models, developers can find...

Teams customize their models to hit their targets for latency, speed, memory, and compute. With the open NVIDIA Nemotron family of models, developers can find the right-sized model for their needs. The new Nemotron 3.5 Lightning NVFP4 checkpoint, for example, preserves accuracy while unlocking up to 4x faster throughput. It’s compressed down to 22 GB from the 66 GB full precision checkpoint…

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